RESEARCH ACHIEVEMENTS

Patents

Date Description Writer Registration
20171130 3,5-Component for prevention and treatment of muscle disease and treatment or muscle function improvement that contains decaf oil quinic acid or chrysanthemum extract Nutribiotech,Yonsei Univ. 10-2017-0162407
20171108 Methods of manufacture of immune-boosting products, including enzyme-treated Noni extracts Nutribiotech,Nutriscience. 10-2017-0147696
20170714 Manufacturing Method for Freeze Dryer of Taheebo Dairy Extraction Nutribiotech,Nutriscience. 10-2017-0089810
20171129 Cream extract or composition to prevent skin aging or improve wrinkles containing solasonin as a valid ingredient. Nutribiotech,Yonsei Univ. 10-2017-0152061
20171130 Purpose intended to prevent and treat position muscular disease and to improve muscle function, including 3,5-dicafeoylquinic acid or chrysanthemum extract. Nutribiotech,Yonsei Univ. PCT/KR2017/013879
20170714 Manufacturing Method for Freezing Dryer of Taheebo or Dried Water Extraction Nutribiotech,Nutriscience. PCT/KR2017/007605
20171101 Methods of manufacture of Taheebo extract Nutribiotech,Nutriscience. PCT/KR2017/012219
20171109 Methods of manufacture of immune-boosting products, including enzyme-treated Noni extracts Nutribiotech,Nutriscience. PCT/KR2017/012679
20181226 Manufacturing Method for Freezing Dryer of Taheebo Dried Water Extraction Nutribiotech,Nutriscience. 16/313,270

Academic papers

Title Journal Writer
Tabetri™ (Tabebuia avellanedae Ethanol Extract) Ameliorates Osteoarthritis Symptoms Induced by Monoiodoacetate through Its Anti-Inflammatory and Chondroprotective Activities (Hindawi) Mediators of Inflammation Jae Gwang Park
Protective Effects of Standardized Siegesbeckia glabrescens Extract and Its Active Compound Kirenol against UVB-Induced Photoaging through Inhibition of MAPK/NF-κB Pathways Journal of Microbiology and Biotechnology Jongwook Kim
In vitro Anti-Inflammatory Activity of Ilex cornuta Extract Mediated by Inhibition of Extracellular Signal-Regulated Kinase Phosphorylation Journal of medicinal food Jisu kim
Characterization and pharmacokinetic study of itraconazole solid dispersions prepared by solvent-controlled precipitation and spray-dry methods Journal of Pharmacy and Pharmacology Taehoon Sim
physicoshemical properities, bioactive composition and antioxidant activities og noni fruit juices from different regions of cultivation The Korean Society of Food Preservation(한국식품저장 유통학회지) Ja min Kim
Effect of Korean Red Ginseng extracts on drug-drug interactions Journal of Ginseng Research Se-Jin Kim
Inhibitory Effects of Curcuma xanthorrhiza Supercritical Extract and Xanthorrhizol on LPS-Induced Inflammation in HGF-1 Cells and RANKL-Induced Osteoclastogenesis in RAW264.7 Cells, Journal of Microbiology and Biotechnology Siyeon Kim
Inhibitory Effect of Standardized Curcuma xanthorrhiza Supercritical Extract on LPS-Induced Periodontitis in Rats, Journal of Microbiology and Biotechnology Kyo Eun Kook
Quantitative determination of xanthorrhizol in rat plasma by HPLC–MS/MS and its application to a pharmacokinetic study Journal of Pharmaceutical and Biomedical Analysis Seungmok Choi
Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus La-14 attenuates Gardnerella vaginalis-infected bacterial vaginosis in mice Nutrients Se-Eun Jang
A simple and reliable analytical method based on HPLC–UV to determine oleanonic acid content in Chios gum mastic for quality control Archives of Pharmacal Research YAN JIN
Tabetri™ (Tabebuia avellanedae Ethanol Extract) Ameliorates Atopic Dermatitis Symptoms in Mice Mediators of Inflammation Jae Gwang Park
Development and Validation of an Analytical Method Readily Applicable for Quality Control of Tabebuia impetiginosa (Taheebo) Ethanolic Extract Journal of AOAC International YAN JIN, KYUNG MIN JEONG, JEONGMI LEE
Production Technology

[ Exclusive Production Line for Probiotics, EPP) ]

The survival rate of probiotics varies greatly depending on environmental influences such as temperature and humidity. Therefore, COSMAX NBT has been studying the environment suitable for the survival of probiotics and has been running Exclusive Production Line for Probiotics (EPP) since 2016.

[ Micro Emulsion Technology ]

COSMAXNBT's micro-emulsion technology increases absorption by making particles smaller by impacting particles in the fluid through particulates, emulsification, and dispersion. We can diversify applications of water-insoluble raw materials and can increase bioavailability with fine particles. Currently, micro-emulsion technology can be applied to the following raw materials.

Nutrient Weight Loss Oral Health Immunity Recovery Etc
Vitamin A CLA Propolis Co-Q10 Royal Jelly Milk Thistle
Vitamin D Phosphatidylserine Octacosanol Plant Sterol
Omega-3 Tumeric Lutein